Curriculum Vitae
Stephen Randal Voss
Department of Biology, University of
Kentucky
Tel: 859-257-9888 Fax: 859-257-1717
SRVOSS@UKY.EDU
1988-1994 Clemson University, Clemson, South Carolina.
PhD, Zoology. Dissertation title:
"Experimental laboratory analyses of ecological and genetic components of
life-history variation in ambystomatid salamanders". Adviser: Dr. David G.
Heckel
1986-1988
Western Carolina University, Cullowhee, North Carolina. MS, Biology.
Thesis title: "The relationship among stream order, length of larval
period, and metamorphosis in the salamander Eurycea wilderae".
Advisor: Dr. Richard C. Bruce.
1982-1986
Francis Marion University, Florence, SC. BS, Biology.
Jun. 2005 - Director,
Ambystoma Genetic Stock Center, University of Kentucky
Jan. 2005 – Associate Professor,
Department of Biology, University of Kentucky
Dec. 2004 – Faculty Associate, Spinal
Cord and Brain Injury Research Center
Aug. 2002 – 2004, Assistant Professor,
Department of Biology, University of Kentucky
Jan. 1999 –Aug. 2002, Assistant
Professor, Department of Biology, Colorado State University.
Sept. 1994 – Dec 1998 Postdoctoral Affiliate, Section of Evolution
and Ecology and Center for Population Biology, University of California at
Davis. Advisor: Dr. Bradley H. Shaffer.
National
Science Foundation, "Collaborative Research: Gauging introgression: Variation across the genome in mode and tempo of natural selection in a tiger salamander hybrid zone", September 2005 - August 2007, $161,648.
National
Science Foundation, “Operational Support for the Ambystoma Genetic Stock
Center”, May 2005 – April 2008, $603,784.
Kentucky Spinal Cord and Head Injury
Research Board, “Microarray and in situ hybridization
analyses of natural spinal cord regeneration.” $300,000, February 2004 –
January 2007).
National Science Foundation Career
Development Award (IBN-0242833; IBN-0080112), Integrative evolutionary research
and education, $490,000, August 2001-July 2006. Includes 3 REU supplements
($5,000 each).
National Institute of Health, National
Center for Research Resources (1 R24 RR16344-01A1), "Genome resources for
model amphibians", $1,440,000, April 2002- March 2007.
National Institute of Health
(1 RO1 HD40165-01), “Developmental genetics of zebrafish metamorphosis”, PI
David Parichy UT-Austin, Co-PI Randal Voss. $1,312, 500, April 2001-2006. I am
serving as a no-cost consultant and collaborator.
National Science Foundation Grant
(IBN-9982719), "Physiological genetics of urodele metamorphosis",
$15,000, August 2000 - August 2001.
Colorado State University Faculty
Research Grant, "Development of genome resources for a model
amphibian", $4500, June 1999 - June 2000.
National Science Foundation Grant,
subcontract of IBN-9509802, $24,875, July 1999 - June 2000.
National Science Foundation Grant,
(co-authored with B. Shaffer, IBN-9509802) "The genetic and physiological
basis of life cycle convergence among Mexican ambystomatids", $292,000,
November 1995 – July 1999.
Highlands Biological Station
Grant-in-Aid, "Population genetics of the shovel-nosed salamander,
Leurognathus marmoratus", $900, August 1995.
R.C. Edwards Fellowship for Outstanding
Graduate Student Research, $5,000, August 1993-May 1994.
National Science Foundation Dissertation
Improvement Grant (BSR-901128), "Genetic basis of paedomorphosis in
ambystomatid salamanders", $12,000, April 1991-August 1993.
North Carolina Nature Conservancy
Grant-in-Aid, "Small mammal community structure on the Henry Wright Nature
Preserve", $430, September-November 1985.
Highlands Biological Station
Grant-in-Aid, "Variation in the timing of metamorphosis in southern
Appalachian populations of the salamander Eurycea wilderae", $1600,
May-August 1985.
National Science Foundation: RCN: Coordinating and enabling the efforts of researchers working with ambystomatid salamanders. April 2006 - March 2011.
Smith, J.J., Kump, K., Walker, J.,
Parichy, D.M., and Voss, S.R. 2005. A genetic linkage map for tiger salamander
and mexican axolotl (Ambystoma): Enabling gene mapping, comparative
genomics, and PCR marker development in Ambystoma.In press,
Genetics.
Jones, M.T., Voss, S.R., Margaret B.
Ptacek, David Weisrock, and David W. Tonkyn. Population genetics and geographic
variation in the shovel-nosed salamander, Desmognathus marmoratus. In press,
Molecular Phylogenetics and Evolution.
Voss, S.R. and J.J. Smith. Evolution of
salamander life cycles: A major effect QTL contributes to both continuous and
discrete variation for metamorphic timing. Genetics170:275-181.
Samuels, AK, D. Weisrock, J.J. Smith, S.
Putta, J. Walker, K. France, and S.R. Voss. 2005. Transcriptional and
phylogenetic analysis of 5 complete ambystomatid salamander mitochondrial
genomes. Gene 349:43-53.
Sri Putta, J.J. Smith, J. Walker, M.
Rondet , D. Weisrock, J. Monaghan, K. Kump, D.C. King, N. J. Maness,
B. Habermann, E. Tanaka, S.V. Bryant, D.M. Gardiner, D.M. Parichy, and S.R.
Voss. 2004. From Biomedicine to Natural History Research: Expressed Sequence
Tag Resources for Ambystomatid Salamanders. BMC Genomics 5:54.
Shaffer,
H.B. Fellers, G.M., Voss, S.R., Oliver J.C., and Pauly, G.B. 2004. Species
boundaries, phylogeography, and conservation genetics of the red-legged frog (Rana
aurora/draytonii) complex. Molecular Ecology 13:2667-2677.
Voss, S.R., K. Prudic, J. Oliver, and
H.B. Shaffer. 2003. Candidate gene analysis of metamorphic timing in
ambystomatid salamanders. Molecular Ecology 12:1217-1223.
Riley, S.P.D., H.B. Shaffer, S.R. Voss,
and B.M. Fitzpatrick 2003. Hybridization between a rare, native tiger
salamander (Ambystoma californiense) and its introduced congener. Ecological
Applications13:1263-1275.
Voss, S.R., J.J. Smith, D.M. Gardiner,
and D.M. Parichy. 2001. Conserved vertebrate chromosomal segments in the large
salamander genome. Genetics 158:735-746.
Voss, S.R. and H.B. Shaffer. 2000.
Evolutionary genetics of metamorphic failure using wild-caught versus
laboratory axolotls (Ambystoma mexicanum). Molecular Ecology
9:1401-1408.
Voss, S.R., H.B. Shaffer, J. Taylor, R.
Safi, and V. Laudet. 2000. Candidate gene analysis of thyroid hormone receptors
in metamorphosing and non-metamorphosing salamanders. Heredity
85:107-114.
Shaffer, H.B., G.M. Fellers, A. Magee,
and S.R. Voss. 2000. The genetics of
amphibian declines: Population substructure and molecular differentiation in
the Yosemite Toad, Bufo Canorus (Anura, Bufonidae) based on SSCP and
mtDNA sequence data. Molecular Ecology 9:245-257.
Parichy, D.M., M. Stigson, and S.R. Voss.
1999. Genetic analysis of steel and the PG-M/Versican-encoding gene AxPG as
candidates for the white (d) pigmentation mutant in the salamander Ambystoma
mexicanum. Development, Genes, and Evolution 209:349-356.
Voss, S.R and H.B. Shaffer. 1997.
Adaptive evolution via a major gene effect: paedomorphosis in the Mexican
axolotl. Proceedings of the National Academy of Sciences 94:
14185-14189.
Voss, S.R. and H.B. Shaffer. 1996. What
insights into the developmental traits of urodeles does the study of
interspecific hybrids provide? International Journal of Developmental
Biology 40:885-893.
Shaffer, H.B. and S.R. Voss. 1996.
Phylogenetic and mechanistic analysis of a developmentally integrated character
complex: alternate life history modes in ambystomatid salamanders. American
Zoologist 36:24-35.
Voss, S.R., D.G. Smith, C.K. Beachy and
D.G. Heckel 1995. Allozyme variation among geographically isolated populations
of the salamander Leurognathus marmoratus. Journal of Herpetology
29:493-497.
Voss, S.R. 1995. Genetic basis of paedomorphosis in the
axolotl, Ambystoma mexicanum: a test of the single gene
hypothesis. Journal of Heredity 86:441-447.
Voss, S.R. 1993. The relationship between
stream order and length of larval period in the salamander Eurycea wilderae.
Copeia 1993:736-742.
Voss, S.R. 1993. Effect of temperature on
body size, developmental stage, and timing of hatching in Ambystoma maculatum.
Journal of Herpetology 27:329-333.
Weisrock, D.W., Shaffer, H.B., Storz, B.L., Storz, S.R., and Voss, S.R. Multiple EST loci provide perspective on mitochondrial DNA polyphyly within and an adaptive radiation of tiger salamanders.Submitted,Molecular Ecology.
Smith, J.J., Staben, C., and Voss, S.R. Salamander Genomics: Linking Fish to Amniotes. In Prep
Theodosiou, M., J.R. Monaghan, S.R. Voss, and D. Noonan. 2005. Impact of NPDC on thyroid receptor signaling FASEB JOURNAL 19 (4): A299.
Voss, S.R. and D.M. Parichy. 2001.
Salamander Genome Project. Axolotl Newsletter 29.
Stigson, M., Parichy, D.M. & Voss,
S.R. 1999. Genetic analysis of PG-M / versican and Steel factor as candidates
for the white (d) gene in the axolotl, Ambystoma mexicanum. In: Regulatory
Processes in Development: The Legacy of Sven Hˆrstadius (Olsson, L. &
Jacobson, C.-O., Eds.). Wenner-Gren International, Portland Press, London.
Voss, S.R., J.J. Smith, and D.M. Parichy.
1999. Towards a genomics resource for evolutionary and developmental studies of
ambystomatid salamanders. American Zoologist 39:11A.
Mason K. A., Parker N. B.,
Parichy D. M. and Voss S. R. Molecular characterization of c- kit from
the Mexican axolotl. Pigment Cell Res. 11, 175A (1998)
Voss, S.R. and H.B. Shaffer. 1998.
Evolutionary genetics of metamorphic failure in the mexican axolotl. American
Zoologist 38:197A.
Voss, S.R. and M. Stigson. 1996. Genetic
linkage analysis and mapping of the gene encoding a PG-M/Versican-like
proteoglycan core protein in relation to the white (d) locus in the mexican
axolotl, Ambystoma mexicanum. In Large Chondroitin Sulfate
Proteoglycans in the Axolotl Embryo, M. Stigson, Ch. V, Pp. 1-9. Acta
Universitais Upsaliensis, Uppsala.
Voss, S.R. 1993. Randomly amplified
polymorphic DNA (RAPD) analysis of ambystomatid salamanders. Axolotl Newsletter
22:28-32.
September 2004 – Southeastern Ecology,
Evolution, and Population Genetics Meeting, Swannanoa, NC (Presented by J.
Smith). “Cross-species effect of a metamorphic timing QTL in ambystomatid
salamanders”.
June 2004 - Society for the Study of
Evolution. Fort Collins, CO. (presented by A. Samuels), “Transcriptional and
phylogenetic analysis of 5 complete ambystomatid salamander mitochondrial
genomes”.
June 2004 - Society for the Study of
Evolution. Fort Collins, CO. (presented by J. Smith), “Comparative Genetics of Amphibian Metamorphosis: Ambystoma
tigrinum species complex”.
June 2004 - 10th
Annual Spinal Cord and Head Injury Research Symposium, Keenland, Lexington, KY,
(Presented with J. Monaghan) “Microarray analysis of natural spinal cord
regeneration”.
May 2004 – NSF EPSCoR Meeting, Lexington,
KY, (Presented by J. Smith) “Comparative Genomics
of Metamorphosis in Ambystomatid Salamanders”.
May 2004 - Invited Seminar: Section of
Integrative Biology, University of Texas, Austin, “Genetics of Hopeful
Monsters”.
May 2004 – Invited Seminar: Centre
College, Danville, KY, “Ambystoma as
an example of adaptive radiation”.
April 2004 – Kentucky Genomics Symposium, Lexington, KY, (Presented by J. Smith)
“Preliminary Assessment of Orthology and Conserved Synteny of Salamander
Genes: Comparisons with Chordate Draft Genomes “.
January 2004 – Invited Seminar: First Okazaki Biology Conference: Biology of Extinction,
Okazaki, JP, “Metamorphic timing in ambystomatid salamanders: Swimming
the thin line between adaptation and extinction”.
November 2003 – Invited Seminar:
Department of Biology, University of Tennessee, “Evolutionary genomics of
ambystomatid salamanders”.
October 2003 – Promotion Seminar:
Department of Biology, University of Kentucky, “Evolutionary genetics and
genomics of ambystomatid salamanders”.
September 2003 – Southeastern Ecology,
Evolution, and Population Genetics Meeting, Lake Sequoia, VA. “Enabling
genomics in non-model organisms”.
September 2003 – Southeastern Ecology,
Evolution, and Population Genetics Meeting, Lake Sequoia, VA. (presented by A.
Samuels) “Comparative genomics of three ambystomatid mitochondrial genomes”.
September 2003 - Southeastern Ecology,
Evolution, and Population Genetics Meeting, Lake Sequoia, VA. (presented by J.
Smith) “Genetic analysis of amphibian sex determination and metamorphic
timing in ambystomatid salamanders.”
June 2003 - Society for the Study of
Evolution. Chico, CA. (presented by B. Fitzpatrick), “Selection in a tiger salamander hybrid zone”.
June 2003 – Invited Seminar:
Metamorphosis Symposium, Joint meeting of Ichthyologists and Herpetologists,
Manaus, Brazil, (presented by B. Shaffer), “Candidate gene analysis of
metamorphic timing”
May 2003 – Center for Ecology, Evolution,
and Behavior Spring Symposium, University of Kentucky, “Genetic analysis of
metamorphic timing in ambystomatid salamanders”.
May 2003 – NSF EPSCoR Meeting, Lexington,
KY, (Presented by J. Walker), “Salamander EST project”.
May 2003 – NSF EPSCoR Meeting, Lexington,
KY, (Presented by A. Samuels) “Salamander mitochondria genome project”.
May 2003 – NSF EPSCoR Meeting, Lexington,
KY, (Presented by K. Kump) “Comparative genome mapping in salamander”.
May 2003 – NSF EPSCoR Meeting, Lexington,
KY, “Integration of a 384 Well Pin Tool into a Tecan Genesis Robotic
WorkStation”.
May 2003 – NSF EPSCoR Meeting, Lexington,
KY, “Comparative EST analysis of regeneration: axolotl limb vs zebrafish
fin”.
May 2003 – Biocomplexity
IV: Regenerative Biology and Medicine Workshop, Bloomington, IN, “Salamander
EST project”.
May 2003 – Biocomplexity
IV: Regenerative Biology and Medicine Workshop, Bloomington, IN, ““Comparative
EST analysis of appendage regeneration: axolotl limb vs zebrafish fin”.
April 2003 – Invited Seminar: Medical
School and IGERT Evo/Devo Group, Indiana University, “Metamorphic failure
and regeneration: Genetic and genomic approaches in axolotl”.
Journals: Evolution and Development, Genetics,Acta
Zoologica Sinica, Copeia, Developmental Dynamics, Embo Reports,
Evolution, Journal of Herpetology, Journal of Molecular Evolution, Lab Animal,
Molecular Ecology, Molecular Vision, Molecular Biology and Evolution, BMC
Ecology
NSF
Evolutionary Genetics grant reviewer
NSF Evolutionary and Ecological
Physiology grant reviewer
NSF BAC Development grant reviewer
NERC grant reviewer
NIH-NCRR, Comparative Medicine grant
reviewer
Austin (TX) Community Foundation
Panels: NIH-NCRR, Comparative Medicine Review
Group 2002
NIH-NCRR, Research Resource Directors
Meeting 2004
NSF Evolutionary Genetics Panel 2004,2005
OTHER SIGNIFICANT ACTIVITIES
Hosted the 30th annual meeting
of the Southeastern Ecology, Evolution, and Population Genetics group at
Swannanoa, NC, October 2004. Approximately 75 undergraduate, graduate students,
post-docs, and faculty attended from universities throughout the southeast and
beyond, including UNC, USC, CU, DU, WFU, UT, UGA, W&L, MSU, and UM, to name
a few.
Joined a group of UK Medical School and Biology
Department faculty that have a NIH T32 training grant on the Cellular and
Molecular Neuroscience of Sensory Systems.
Share laboratory space (BBSRB) and collaborate with core faculty and associates of the UK Spinal Cord and Head Injury Research Center.
Maintain the Salamander Genome Project
Website (http://salamander.uky.edu).
Maintain the Salamander EST database (http://ambystoma.uky.edu/ESTdb).
Direct the Ambystoma Genetic Stock Center at UK, an NSF-funded living stock resource (http://bigapple.uky.edu/~axolotl).
Currently in Voss Lab:
James
Monoghan, PhD student
Jeramiah
Smith, received MS under me at CSU, PhD student
Amy
Samuels, MS student
Sri Putta , Computer Sciences, now a full-time bioinformaticist
Kevin Kump, undergraduate researcher in my lab at UK, now a tech
Robert Page, PhD student
Shawn, undergraduate student
Formerly in Voss Lab:
John
Niedzwiecki, PhD student, currently pursuing a Post-doc at U. Cincinnati
Jonathan Hobbs,
undergraduate researcher, trying for med school
Sameera
Dasari, UK-MCB rotation student, currently pursuing a PhD at UK
Thomas
Babcock, undergraduate CSU researcher, currently pursuing Vet School admission
Rebecca
Hart, HHM undergraduate CSU researcher, currently an undergrad at CSU
David King,
undergraduate CSU researcher, currently a PhD student at Penn State U
David Lehman,
undergraduate CSU researcher, currently a medical student at Rochester U
Nick Maness,
undergraduate CSU researcher, currently a PhD student at U. Wisconsin
Tim Sesterhenn, PhD student in Biology
Stephen
Coleman, MS student in Veterinary Sciences
Amanda
Ensminger, PhD student in Biology
Xiaohua Yan, PhD student in Biology
Debasish
Ghosh, PhD student in Biology
James Monoghan, PhD
student in Biology
Gennie
Lintecum, MS student in Biology, defended, UK
Weixi
Li, PhD student in Biology
Jeramiah
Smith, PhD student in Biology
Amy
Samuels, PhD student in Biology
Gennie
Lintecum, MS student in Biology, defended, UK
Cheryl Perkins, Environmental Health MS
student, defended, CSU
Paul Sims, Biology MS student, defended,
CSU
Adam Holmes, Cell and Molecular Biology PhD
student, CSU
Jeramiah Smith, Biology MS student,
defended, CSU
David Logue, Biology PhD student, CSU
Linda Courter, Biology MS student, CSU
Xiaoli Yu, CMB and Biology PhD student,
defended, CSU
Paul Lucas, Fisheries and Wildlife PhD
student, CSU
POSTDOCS
AND RESEARCH SCIENTISTS
Currently
in Voss Lab
John
Walker, Research Scientist
Dave
Weisrock, Post doc